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Selection should reflect the clinical reason, evidence, product quality, tolerance and route-related risk

The medication is still effective, the timeline is just shifted

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A repeated measures MANCOVA (intent-to-treat analysis, carrying forward data from individuals who dropped out of the study) tested weekly changes over time, including comorbidity (major depressive disorder, obsessive compulsive disorder, posttraumatic stress disorder and generalized anxiety disorder) and medication use (antidepressant and antipsychotic use) in the model